Sema3A signaling molecule found to have significant cartilage-protective effects in osteoarthritis

Osteoarthritis (OA), a common degenerative joint disease that affects millions of people worldwide, particularly targets the knee joint. Over time, the cartilage within the joint wears down, leading to damage in the underlying bone and resulting in pain, inflammation, and reduced function. A key mystery of OA is the process where both cartilage wear and abnormal nerve growth cause pain in the joint.

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