Safe new target against acute myeloid leukemia discovered

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is the main finding of the latest research by Dr. Marcus Buschbeck and Dr. René Winkler, researchers at the Josep Carreras Leukaemia Research Institute. Experimental results confirm that the removal of any of the three proteins of the macroH2A family of histones, linked to acute myeloid leukemia, is well tolerated in mice and has no major effect on their health.

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