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Overabundance of HMGN1 protein may explain congenital heart defects in Down syndrome

Overabundance of HMGN1 protein may explain congenital heart defects in Down syndrome

Three copies of chromosome 21 cause Down syndrome (DS), and roughly half of children born each year in the United States with DS—approximately 2,600—also have congenital heart defects (CHDs).

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