Surprising new roles discovered for known blood cancer gene DNMT3A

A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates mutations—which might occur with age or due to environmental exposures such as smoking—a person's risk of developing blood cancers such as acute myeloid leukemia (AML) increases.

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