'Molecular glue' harnesses the power of the immune system to treat neuroblastoma

Gene expression governs whether neuroblastoma tumor cells exist in either the adrenergic (differentiated and sensitive to treatment) or mesenchymal (less differentiated and therapy-resistant) cell state. Tumors may switch between states, confounding treatment efforts. A study from St. Jude Children's Research Hospital indicates that the extent of this plasticity is underreported, but there is a way to circumvent this challenge therapeutically.

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