Surprising gene activity shields certain nerve cells from ALS damage

By analyzing millions of messenger RNA molecules (mRNA) during the course of ALS, researchers at Stockholm University, in collaboration with scientists at the Paris Brain Institute and Örebro University, have identified why certain nerve cells are resistant to the disease and what happens in the sensitive nerve cells when they are affected. The study, published in the journal Genome Research, focuses on a hereditary form of ALS caused by mutations in the SOD1 gene.

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