Common intracellular toxin could help fight leukemia

All cells naturally produce formaldehyde as a byproduct of metabolism. To survive this toxic stress, both healthy and cancerous blood-forming cells rely on a built-in defense system. Now, scientists at the Lewis Katz School of Medicine at Temple University have discovered that leukemia cells generate far greater amounts of formaldehyde than normal blood cells and that to survive this stress, they rely on a unique protective mechanism.

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