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Unlocking the Naᵥ1.9 channel: A hidden switch in pain and itch disorders

Unlocking the Naᵥ1.9 channel: A hidden switch in pain and itch disorders

Imagine not feeling any pain when you stub your toe—or, conversely, experiencing constant burning pain or itching without an obvious cause. For some people, this is reality, caused by mutations in a single protein: the sodium channel NaV1.9.

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