How an Alzheimer's peptide and a blood protein may combine to drive early disease pathology

Scientists have long known that the Alzheimer's brain often features abnormal plaques and tangles, and recent studies have highlighted the role that the brain's vascular system plays in disease progression. But for decades, this knowledge has failed to translate into fully effective treatments. The lack of progress is largely due to the fact that, despite landmark findings, the precise pathway of neurodegeneration is still unclear.
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