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Sunday, July 13, 2025
Spleen-based islet transplantation restores glycemic control in type 1 diabetes without full immunosuppression
Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression. Nanoparticle-driven spleen remodeling allowed transplanted mouse, rat, and human islets to restore normal blood sugar in diabetic rodents and cynomolgus macaques.
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