Overexpressing miRNA-27a in human dental pulp stem cells yields anti-inflammatory effect, may regenerate tissue

Dental caries (tooth decay) is a common oral health condition that often causes significant pain and discomfort and may even lead to tooth loss. In severe and untreated cases, bacterial infection combined with the host's immune response can cause bone resorption, or the breakdown of bone tissue in the tooth root. Moreover, traditional treatments for advanced dental caries, such as surgery, can result in bone defects that require complex bone grafting procedures.

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