Signals from dying cells may spur liver regeneration after acetaminophen injury

Acetaminophen is the most frequently taken fever and pain medication worldwide, but overdosing can be toxic to liver cells. In the United States, about 1,600 cases of acute liver failure and 500 deaths occur each year due to acetaminophen overuse and liver failure. Although the liver has a remarkable potential to regenerate and recover from injury, scientists are seeking to better understand how this happens after acetaminophen toxicity.

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