Experts challenge aspirin guidelines based on their undue reliance on a flawed trial

Recent guidelines have restricted aspirin use in the primary prevention of cardiovascular disease. The American Heart Association (AHA)/American College of Cardiology (ACC) guidelines restricted aspirin to patients under 70, and more recently, the United States Preventive Services Task Force restricted aspirin use to patients under 60. However, heart attack and stroke risks both rise with age, leaving health care providers unsure about when to stop prescribing aspirin, whether it should be used for primary prevention, and which patients would benefit most.

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