3D gene hubs: Researchers find DNA folding in brain cell nuclei may be key to understanding glioblastoma cancer

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell Medicine researchers. The findings, published April 3 in Molecular Cell, offer a new way to think about cancer beyond gene mutations, based on the way that genes are connected and regulated in three-dimensional space.

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