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Removing a protein 'signal jammer' improves tumor response to immunotherapy

Removing a protein 'signal jammer' improves tumor response to immunotherapy

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) as a signal jammer to prevent the body's anticancer systems from communicating with the immune system.

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