Lab-grown liver model offers a platform to study fibrosis and regeneration

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments. The model recreates interactions between hepatocytes and hepatic stellate cells, two cell types involved in liver repair and fibrosis. It provides a much-needed, human-based platform to study how liver scarring develops, how cells communicate during injury, and to test drugs that could halt or even reverse liver damage.

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